1Division of Critical Care Medicine, Department of Medicine, Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada.
2Department of Health and Exercise Sciences, University of British Columbia – Okanagan, Kelowna, BC, Canada.
3Department of Clinical Neurosciences, Addenbrookes Hospital, University of Cambridge, Cambridge, United Kingdom.
4Department of Anaesthesiology, Pharmacology and Therapeutics, Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada.
5Division of Neurosurgery, Department of Surgery, Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada.
6Centre for Clinical Epidemiology and Evaluation, Vancouver Coastal Health Research Institute, University of British Columbia, Vancouver, BC, Canada.
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Supported, in part, by grant from the Laerdal Foundation.
Dr. Sekhon’s institution received funding from Laerdal Foundation; he received funding from the Clinician Scientist Award from Vancouver Coastal Health Research Institute. Dr. Menon received support for article research from National Institute for Health Research, United Kingdom. Dr. Gooderham received funding from consulting for Stryker Canada and Baxter Canada, and research grants from Brain Aneurysm Foundation and Rare Diseases Foundation (research into Moyamoya disease). Dr. Griesdale is funded through a Health-Professional Investigator Award from the Michael Smith Foundation for Health Research. The remaining authors have disclosed that they do not have any potential conflicts of interest.
Trial Registration: NCT03609333—ClinicalTrials.gov.
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