1Department of Adult Critical Care, Guy’s and St Thomas’ NHS Foundation Trust, King’s Health Partners, London, UK.
2Division of Centre of Human Applied Physiological Sciences, King’s College London, London, UK.
3Department of Emergency and Organ Transplants (DETO), Anesthesiology and Intensive Care, Università degli Studi di Bari “Aldo Moro”, Bari, Italy.
4Department of Biomedical Sciences and Human Oncology, Chair of Medical Statistics, Università degli Studi Aldo Moro, Bari, Italy.
5Instituto de Investigación Sanitaria del Principado de Asturias, Oviedo, Spain.
6Centro de investigación biomédica en Red-Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.
7Cardiac Critical Care Unit, University Central Hospital of Asturias, Oviedo, Spain.
8Department of Functional Biology, University of Oviedo, Oviedo, Spain.
9Peter Gorer Department of Immunobiology, School of Immunology & Microbial Sciences, King’s College, London, UK.
Drs. Camporota, Caricola, Bartolomeo, and Grasso contributed to the full access to all the data in the study and responsibility for the integrity of the data. Drs. Camporota, Caricola, Bartolomeo, Shankar-Hari, and Grasso contributed to the access to database, data analysis, and interpretation. Drs. Camporota and Grasso contributed to the study concept and design. Drs. Camporota, Caricola, and Grasso contributed to the responsibility for data acquisition. Drs. Camporota, Amado-Rodriguez, Vasques, and Grasso contributed to the article preparation and drafting. Drs. Camporota, Caricola, Di Mussi, Wyncoll, Meadows, Amado-Rodriguez, Vasques, Sanderson, Glover, Barrett, and Grasso critically revised the article for important intellectual content. Drs. Camporota and Barrett contributed to the statistical analysis.
Dr. Wyncoll received funding for paid talks from Pfizer, MSD, and Fisher and Paykel. Dr. Grasso’s institution received funding from Orion Pharma, Italy, and he received funding from Maquet, Italy. The remaining authors have not disclosed any potential conflicts of interest.
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