Feature Articles

Quality of Life and 1-Year Survival in Patients With Early Septic Shock: Long-Term Follow-Up of the Australasian Resuscitation in Sepsis Evaluation Trial

Higgins, Alisa M. MPH, GDipBiostat, BPhysio(Hons)¹; Peake, Sandra L. BM, BSc(Hons), FCICM, PhD^1,2; Bellomo, Rinaldo AO, MBBS, MD, PhD, FRACP, FCICM, FAMHS^1,3; Cooper, D. Jamie AO, BMBS, MD, FRACP, FCICM, FAHMS^1,4; Delaney, Anthony PhD, FACEM, FCICM^1,5; Harris, Anthony H. MSc⁶; Howe, Belinda D. MPH¹; Nichol, Alistair D. PhD, JFICMI, FCARCSI, FCICM^1,4,7; Webb, Steve A. PhD, FCICM, FRACP^1,8; Williams, Patricia J. BN Practice-Int care^1,2; on behalf of the Australasian Resuscitation in Sepsis Evaluation (ARISE) Investigators and the ANZICS Clinical Trials Group

Author Information

¹Australian and New Zealand Intensive Care Research Centre, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, VIC, Australia.

²Department of Intensive Care Medicine, The Queen Elizabeth Hospital, University of Adelaide, Adelaide, SA, Australia.

³Department of Intensive Care, Austin Health, Melbourne, VIC, Australia.

⁴Department of Intensive Care and Hyperbaric Medicine, The Alfred, Melbourne, VIC, Australia.

⁵Department of Intensive Care, Royal North Shore Hospital and University of Sydney, Sydney, NSW, Australia.

⁶Centre for Health Economics, Monash University, Melbourne, VIC, Australia.

⁷School of Medicine and Medical Sciences, University College Dublin, Dublin, Ireland.

⁸Department of Intensive Care, Royal Perth Hospital and University of Western Australia, Perth, WA, Australia.

Investigators in the Australasian Resuscitation in Sepsis Evaluation (ARISE) study and their affiliations are listed in Supplemental Digital Content 1 (https://links.lww.com/CCM/E509).

Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s website (http://journals.lww.com/ccmjournal).

The Australasian and Resuscitation in Sepsis Evaluation trial was funded by the National Health and Medical Research Council of Australia (numbers 491075 and 1021165). Additional funding to support the long-term mortality and health-related quality of life assessments was provided by the Intensive Care Foundation.

Ms. Higgins was supported to complete this work by a National Health and Medical Research Council postgraduate scholarship (number 579709). The remaining authors have disclosed that they do not have any potential conflicts of interest.

Clinical trial registration: ClinicalTrials.gov number, NCT00975793.

For information regarding this article, E-mail: [email protected]

Critical Care Medicine 47(6):p 765-773, June 2019. | DOI: 10.1097/CCM.0000000000003762