1Adult Critical Care Directorate, St George’s University Hospitals NHS Foundation Trust and St George’s University of London, London, United Kingdom.
2Institute of Infection and Immunity, St George’s University of London, London, United Kingdom.
Preliminary results were presented at the International Symposium of Intensive Care and Emergency Medicine (ISICEM), Brussels 2015.
Current controlled trials registration number: NCT02569008.
Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s website (http://journals.lww.com/ccmjournal).
Dr. Aya received funding from Applied Physiology and LiDCO. Dr. Fletcher disclosed other support (payment received by his institution from BARD for educational course). Dr. Cecconi received funding from Edwards Lifesciences, LiDCO, Deltex, Applied Physiology, Masimo, Bmeye, Cheetah, Imacor (travel expenses, honoraria, advisory board, unrestricted educational grant, research material). He disclosed other support (Consultations for LiDCO Edwards Lifesciences). The remaining authors have disclosed that they do not have any potential conflicts of interest.
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