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Necrotizing soft-tissue infections

Section Editor(s): Sevransky, Jonathan E. MD, MHSUstin, Jeffrey S. MS, MD; Malangoni, Mark A. MD, FACS


In the article on page 2156 of the September issue, in Table 1, the adult intravenous dose for doxycycline is listed as 1 gm q12h. The correct dose is 100 mg q12h.

Critical Care Medicine. 39(11):2592, November 2011.

doi: 10.1097/CCM.0b013e31821cb246
Concise Definitive Review

Objective: To provide a contemporary review of the diagnosis and management of necrotizing soft-tissue infections.

Data Sources: Scientific literature and internet sources.

Study Selection: Major articles of importance in this area.

Conclusions: The mortality for necrotizing soft-tissue infections appears to be decreasing, possibly due to improved recognition and earlier delivery of more effective therapy. Establishing a diagnosis and initiating treatment as soon as possible provides the best opportunity for a good outcome.

From the Department of Surgery, Division of Trauma, Burns, and Critical Care, Case Western Reserve University, MetroHealth Medical Center Campus, Cleveland, OH.

The authors have not disclosed any potential conflicts of interest.

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© 2011 by the Society of Critical Care Medicine and Lippincott Williams & Wilkins