From the Intensive Care Unit (CL), Hospital Universitario de Valme, Universidad de Sevilla, Sevilla, Spain; Intensive Care Unit (R-S, AH-V), Hospital Universitario Dr. Negrín, Universidad de las Palmas de Gran Canaria, Spain; Mathematics Department (PS), Universidad de las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain; Intensive Care Unit (BG), Hospital Universitario La Paz, Madrid, Spain; Intensive Care Unit (AB), Hospital Central de Asturias, Oviedo, Spain; Service of Clinical Microbiology (CC, EM), Hospital Universitario de Valme, Universidad de Sevilla, Sevilla, Spain; Intensive Care Unit (CB), Hospital Interzonal General de Agudos, San Martín de la Plata, Argentina; Intensive Care Unit (AU-V), Hospital Universitario Miguel Servet, Zaragoza, Spain; Intensive Care Unit (FJGDM), Hospital Mútua de Terrassa, Terrassa, Barcelona, Spain; Intensive Care Unit (AB), Hospital Severo Ochoa, Leganés, Madrid, Spain; Intensive Care Unit (MJL), Hospital General Yagüe, Burgos, Spain; and Service de Réanimation Médicale (PEC), Hôpital Le Bocage, Dijon, France.
Supported, in part, by a grant from Gilead Sciences, S.L., Madrid, Spain. Gilead Sciences had no role in the collection, analysis, or interpretation of data or in the decision to submit the study for publication.
The authors have not disclosed any potential conflicts of interest.
Study concept and design: León, Ruiz-Santana, Saavedra, Charles; Acquisition of data: León, Ruiz-Santana, Saavedra, Galván, Blanco, Balasini, Utande, González, Blasco-Navalproto, López, Charles, Hernández-Viera; Analysis and interpretation of data: León, Ruiz-Santana, Saavedra, Charles; Drafting of the manuscript: León, Ruiz-Santana, Saavedra, Galván, Blanco, Castro, Balasini, Utande-Vázquez, González, Blasco-Navalproto, López, Charles, Martín, Hernández-Viera; Critical revision of the manuscript for important intellectual content: León, Ruiz-Santana, Saavedra; Statistical analysis: Saavedra; Obtained funding: León; Administrative, technical, or material support: León, Ruiz-Santana, Saavedra, Galvan Castro, Martin; Study supervision: León, Ruiz-Santana, Saavedra, Charles; Approval of the final draft: León, Ruiz-Santana, Saavedra, Galván, Blanco, Castro, Balasini, Utande-Vázquez, González de Molina, Blasco-Navalproto, López, Charles, Martín, Hernández-Viera.
Presented, in part, at the 47th Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, IL, September 17–20, 2007.
Dr. León had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
For information regarding this article, E-mail: [email protected]