From the Section of Critical Care Medicine, Health Sciences Centre/St. Boniface Hospital, University of Manitoba, Winnipeg, MB, Canada (AK, DR, BL, SS, RS); Section of Pulmonary and Critical Care Medicine, University of Wisconsin Hospital and Clinics, Madison, WI (KEW); Cooper Hospital/University Medical Center, Robert Wood Johnson Medical School, UMDNJ, Camden, NJ (JEP, SZ); St. Agnes Medical Center, Baltimore, MD (DF); Section of Pulmonary and Critical Care Medicine, Rush-Presbyterian-St. Luke's Medical Center, Chicago, IL (LT, DG); Laurentian University, Biomolecular Sciences Program and Department of Chemistry and Biochemistry, Sudbury, ON (AK); and Biostatistical Consulting Unit, Department of Community Health Sciences, University of Manitoba, Winnipeg, MB (MC).
Supported, in part, by unrestricted grants from Eli-Lilly, Pfizer, Merck, and Astra-Zeneca. Additional support was provided by the Health Sciences Centre Department of Research and Health Sciences Centre Foundation. Companies that provided partial grant support for this project had no role in study design; collection, analysis, or interpretation of data; writing of the report; or the decision to submit the work for publication.
Dr. Kumar has received honoraria for lectures from Eli-Lilly and Co. and Merck and Co. He has also received grant support for this project as noted. Dr. Light is a consultant for Eli-Lilly and Co. Dr. Parrillo has received research grants from GlaxoSmithKline for porcine/human research on sepsis; he also holds grants from Arginox, DeepBreeze, and Minimitter. Dr. Parrillo is also on Advisory Boards for Edwards, GlaxoSmithKline, and OrthoBioTech (Johnson & Johnson). The remaining authors do not have any conflicts of interest to disclose.
Address requests for reprints to: Anand Kumar, MD, E-mail: [email protected]