Original Articles: PDF OnlyChanges in hepatic flow induced by continuous positive pressure ventilation in critically ill patientsBONNET, F. MD; RICHARD, C. MD; GLASER, P. MD; LAFAY, M. MD; GUESDE, R. MD Author Information From the Département d'Anesthésie, C.H.U. Pitié Salpétrière, Paris, France. Critical Care Medicine 10(11):p 703-705, November 1982. Buy Abstract To quantify the influence of continuous positive pressure ventilation (CPPV) on hepatic plasma flow (HPF) in 8 critically ill patients submitted to controlled ventilation, we measured simultaneously HPF by the indocyanine green dye (IGD) clearance and cardiac output (CO) by the thermodilution technique, while increasing PEEP from 0–20 cm H2O. CPPV induced a significant decrease in HPF which was related to the level of PEEP. A linear correlation was documented between HPF and CO; HPF remained a constant fraction of CO during CPPV. These results suggest that the decrease in CO is the most likely mechanism of the fall in HPF during CPPV. Copyright © by 1982 by the Society of Critical Care Medicine and Wolters Kluwer Health, Inc. All Rights Reserved.