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Letter to the Editor

Tracheostomy for Coronavirus Disease 2019 Patients: Maintaining the Standard of Care

Bassily-Marcus, Adel MD; Leibner, Evan S. MD, PhD; Kohli-Seth, Roopa MD

Author Information
Critical Care Explorations: August 2020 - Volume 2 - Issue 8 - p e0190
doi: 10.1097/CCE.0000000000000190
  • Open
  • COVID-19

Abstract

To the Editor:

Tracheostomy is a common procedure performed for ICU patients to replace the translaryngeal intubation when patients need prolonged mechanical intubation or fail short term weaning from ventilator. For many, it is a lifesaving intervention that is the only way for patients to regain their respiratory independence. This is particularly true when critical illness leads to the significant physical deconditioning that necessitates prolonged weaning from mechanical ventilation.

The use of tracheostomy as an alternative to continued translaryngeal intubation offers several advantages. It can improve patient comfort and decrease need for sedation and pain medications; hence, less delirium. Tracheostomy also allows for early mobility, shorter duration of mechanical ventilation, and shorter ICU and hospital stay. In addition, tracheostomy provides better oral hygiene, less injury (dental, laryngeal, and tracheal injury), and easier and safer nursing care. In the event of unsuccessful reintubation due to a difficult airway, the lack of a secure airway that tracheostomy affords, can be lethal.

Despite the many advantages of tracheostomy, there is a lack of consensus on the optimal timing for tracheostomy placement. Timing of tracheostomy placement has been controversial with most defining early tracheostomy as 2–10 days and late tracheostomy 7–14 days from intubation. Of note, no studies have evaluated the effect of delaying tracheostomy to later than 21 days, we consider this time a very late tracheostomy. The benefits of earlier timing include more ventilator-free days (1,2), shorter sedation duration (3), and shorter ICU length of stay; possible decreased mortality has been demonstrated in a recent meta-analysis (3). In Cochran’s review of eight randomized controlled trials, mortality benefit was demonstrated for the early tracheostomy (< 10 d) (4).

With the rapidly expanding coronavirus disease 2019 (COVID-19) pandemic, a sharp rise in patients requiring prolonged mechanical ventilation led to the subsequent increase in need for tracheostomy for these patients. Due to the risk of viral transmission to staff with aerosolizing procedures (arguably the most aerosolizing procedure is during tracheostomy placement), multiple international professional otolaryngology and surgical organizations (5–7) published guidelines recommending delaying tracheostomy placement to after 21 intubation days in order to ensure viral clearance prior to the procedure. In the setting of these well-intended practice guidelines, there has been practice dilemma when intensivists who manage COVID-19 patients identify the need for earlier tracheostomy, and the guidelines recommend a “pause.” The impact of delays in performing tracheostomy is well known to intensivists. Undoubtedly, delaying tracheostomy leads to prolonged use of sedatives and analgesics with the subsequent increased risk of delirium (an independent risk for mortality), increasing risk of unplanned extubation and airway emergencies, more prolonged duration of mechanical ventilation, increased ICU stay, delay in mobility with increasing ICU acquired weakness, and increased risk of post intensive care syndrome. Often tracheostomy comes as the only viable solution when weaning from the ventilator requires multi-stepped approach, compared to the all or none approach with extubation. This is often clear, particularly for patients who are deconditioned after prolonged critical illness such as COVID-19 pneumonia with acute respiratory distress syndrome.

A clear solution in our organization was utilization of the already established Institute for Critical Care Medicine Tracheostomy Team (ICCM-TT), with its multidisciplinary members from departments including Surgery, Critical Care, Cardiac Surgery, Thoracic Surgery, and Otolaryngology. In the nine ICUs dedicated to the management of COVID-19 critical care patients in April 2020, the ICCM-TT performed 111 tracheostomy procedures. Case selection for all procedures involves multidisciplinary team evaluation and factors patient medical stability, with patient’s wishes after discussing goals of care. Median time from translaryngeal intubation to tracheostomy was 11 days. All cases were performed at bedside, using percutaneous dilatational technique (PDT) with bronchoscopic guidance using a single-use bronchoscopes. Prior to COVID, PDT was the standard for the majority of tracheostomies performed for intubated ICU patients at Mount Sinai Hospital. PDT has long been accepted as the standard of care (8), together with the familiarity of the team with PDT technique, and the utilization of real-time ultrasound guidance in cases identified to have difficult anatomical landmarks made the decision to perform PDT a clear choice. Additional advantage in COVID-19 patients, there is less exposure to open respiratory epithelium in PDT compared to open technique. A modification from the standard PDT technique was to minimize interruption of the ventilator circuit and holding ventilation anytime the circuit needed to be disrupted, similar to other reports (7).

Results of this approach have yielded the following patient outcomes to date: 66 patients (59%) were discharged alive, 41 patients (37%) expired, and the remaining four patients (4%) were weaned from mechanical ventilation (no ventilatory support, downsized tracheostomy tube, or decannulated) but still hospitalized on non-ICU floors (Fig. 1). All of the 111 procedures were performed within 1 day of the tracheostomy requests unless medical instability mandated postponing of the procedure or revisiting goals of care.

F1
Figure 1.:
Sixty days outcome of 111 coronavirus disease 2019 (COVID-19) patients who received tracheostomy in April 2020. Demonstration of number and percentages of patients discharged alive (66, 59%), expired (41, 37%), and remained hospitalized (4, 4%). All four remaining hospitalized patients were weaned from mechanical ventilation.

Regarding staff outcomes, none of the ICCM-TT members acquired COVID-19 infections, no one has shown symptoms of COVID-19, and additionally, all have tested negative for antibodies. The concern of increased risk of transmission of infection to providers from PDT with potentially active infection can be minimized using proper personal protective equipment (PPE) and training without delaying the needed procedure. Of note, powered air purifying respirator (PAPR) devices were dedicated to the ICCM-TT to be used during the PDT. The safe performance of the PDT was likely due to the thorough pre-procedural planning, adherence to ICCM-TT protocols, and vigilance in maintaining infection control guidelines. It is not clear if the use of PAPR added another layer of safety, but it required additional training on donning and doffing as well as proper disinfection between procedures, these were strictly followed.

The recommendation to delay tracheostomy to a new category, the very late tracheotomy after 21 days is asking for a significant change in the standard of care with no data to support such recommendations. As medical specialties respond to the immediate COVID-19 surge and thereby gain experience in its management, analysis of outcomes will shape our future protocols. Based on standard guidelines that describe the benefits of tracheostomy to overall care and our own experiences during COVID-19, we advocate that tracheostomy placement should not be delayed. The availability of the experienced dedicated team (ICCM-TT), strictly following strategies and protocols and the proper PPE use, modification of the technique, allowed performing the procedure when needed instead of delaying it to mitigate the risk of viral transmission.

REFERENCES

1. Dochi H, Nojima M, Matsumura M, et al. Effect of early tracheostomy in mechanically ventilated patients. Laryngoscope Investig Otolaryngol. 2019; 4:292–299
2. Tai HP, Lee DL, Chen CF, et al. The effect of tracheostomy delay time on outcome of patients with prolonged mechanical ventilation: A STROBE-compliant retrospective cohort study. Medicine (Baltimore). 2019; 98:e16939
3. Hosokawa K, Nishimura M, Egi M, et al. Timing of tracheotomy in ICU patients: A systematic review of randomized controlled trials. Crit Care. 2015; 19:424
4. Andriolo BN, Andriolo RB, Saconato H, et al. Early versus late tracheostomy for critically ill patients. Cochrane Database Syst Rev. 2015; 1:CD007271
5. Michetti CP, Burlew CC, Bulger EM, et al.; Critical Care and Acute Care Surgery Committees of the American Association for the Surgery of Trauma. Performing tracheostomy during the Covid-19 pandemic: Guidance and recommendations from the Critical Care and Acute Care Surgery Committees of the American Association for the Surgery of Trauma. Trauma Surg Acute Care Open. 2020; 5:e000482
6. Parker NP, Schiff BA, Fritz MA, et al. Tracheotomy Recommendations During the COVID-19 Pandemic. 2020, Alexandria, VA: Airway and Swallowing Committee of the American Academy of Otolaryngology-Head and Neck Surgery. Available at: https://www.entnet.org/content/tracheotomy-recommendations-during-covid-19-pandemic. Accessed August 11, 2020
7. Chao TN, Braslow BM, Martin ND, et al.; Guidelines from the COVID-19 Tracheotomy Task Force, a Working Group of the Airway Safety Committee of the University of Pennsylvania Health System. Tracheotomy in ventilated patients with COVID-19. Ann Surg. 2020; 272:e30–e32
8. Kornblith LZ, Burlew CC, Moore EE, et al. One thousand bedside percutaneous tracheostomies in the surgical intensive care unit: Time to change the gold standard. J Am Coll Surg. 2011; 212:163–170
Keywords:

coronavirus disease 2019; timing; tracheostomy

Copyright © 2020 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the Society of Critical Care Medicine.