Article: PDF OnlyWaal-Manning H. J.; Paulin, J. M.; Wallis, A. T.; Simpson, F. O.Journal of Cardiovascular Pharmacology: 1990 - p S87-S88 Free Abstract Summary The data for patients referred to the Dunedin Hypertension Clinic (975 men, 1,348 women) between 1953 and 1977 have been examined by the Cox proportional hazards method for significant age-corrected predictors of 8-year cardiovascular and total mortality. For men, some significant predictors were systolic and diastolic blood pressure (BP), indices of target organ damage (heart and eyes) and smoking at presentation, and achieved BP and serum cholesterol at follow-up. For women, serum cholesterol, diabetes, target organ damage (heart and eyes) and smoking at presentation, and achieved BP level at follow-up were predictors. Relative risk for total or cardiovascular mortality was increased in both sexes most by smoking and by increased levels of achieved BP. Copyright © 1990 Wolters Kluwer Health, Inc. All rights reserved.