It has been observed in many studies that the risk of CAD and acute MI is higher in people with vitamin D deficiency 13–15. The possible mechanism between vitamin D insufficiency and cardiac events has been postulated to be associated with metabolic, procoagulant, and inflammatory events. This suggests that vitamin D insufficiency increases the risk of acute MI by promoting established risk factors that are predisposed to atherothrombosis 16.
As the design of the study was case-controlled and only collected new, eligible cases of acute hospitalized MI, the sample size was relatively small, which in part could explain the nonstatistically significant difference in vitamin D levels between groups despite the higher clinical rate of vitamin D deficiency in acute MI cases.
In addition to the Duhok Heart Center, the authors acknowledge the Azadi laboratory staff in Duhok for their help in carrying out this study.
There are no conflicts of interest.
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