Review ArticlesCharacteristics and Outcomes of Patients 80 Years and Older Hospitalized With Coronavirus Disease 2019 (COVID-19)Nabors, Christopher MD, PhD*; Sridhar, Abhinaya MD*; Hooda, Urvashi MD*; Lobo, Stephen A. MD*,†; Levine, Avi MD‡; Frishman, William H. MD*; Dhand, Abhay MD*,§Author Information From the Departments of *Medicine †Infection Prevention and Control ‡Cardiology, Westchester Medical Center and New York Medical, College, Valhalla, NY §Transplant Infectious Diseases, Westchester Medical Center and New York Medical, College, Valhalla, NY. Disclosure: The authors declare no conflict of interest. Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s Website (www.cardiologyinreview.com). All authors verify that they had access to the data and a role in writing the manuscript Correspondence: Christopher Nabors, MD, PhD, Westchester Medical Center, Taylor Care Pavilion, Room C316, 100 Woods Road, Valhalla NY 10595. E-mail: [email protected]. Cardiology in Review: January/February 2021 - Volume 29 - Issue 1 - p 39-42 doi: 10.1097/CRD.0000000000000368 Buy SDC Metrics Abstract Patients older than 65 years hospitalized with COVID-19 have higher rates of intensive care unit admission and death when compared with younger patients. Cardiovascular conditions associated with COVID-19 include myocardial injury, acute myocarditis, cardiac arrhythmias, cardiomyopathies, cardiogenic shock, thromboembolic disease, and cardiac arrest. Few studies have described the clinical course of those at the upper extreme of age. We characterize the clinical course and outcomes of 73 patients with 80 years of age or older hospitalized at an academic center between March 15 and May 13, 2020. These patients had multiple comorbidities and often presented with atypical clinical findings such as altered sensorium, generalized weakness and falls. Cardiovascular manifestations observed at the time of presentation included new arrhythmia in 7/73 (10%), stroke/intracranial hemorrhage in 5/73 (7%), and elevated troponin in 27/58 (47%). During hospitalization, 38% of all patients required intensive care, 13% developed a need for renal replacement therapy, and 32% required vasopressor support. All-cause mortality was 47% and was highest in patients who were ever in intensive care (71%), required mechanical ventilation (83%), or vasopressors (91%), or developed a need for renal replacement therapy (100%). Patients older than 80 years old with COVID-19 have multiple unique risk factors which can be associated with increased cardiovascular involvement and death. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.