New Therapy UpdateThe Firehawk Stent: A Review of a Novel Abluminal Groove-Filled Biodegradable Polymer Sirolimus-Eluting StentSaito, Yuichi MD*; Grubman, Daniel BA*; Cristea, Ecaterina MD*; Lansky, Alexandra MD*,†Author Information From the *Division of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT †Department of Cardiology, Barts Heart Centre, London and Queen Mary University of London, London, UK. Disclosure: A.L. has received a research grant and speaker fee from Microport. The other authors have no conflicts of interest to report. Correspondence: Alexandra Lansky, MD, Division of Cardiovascular Medicine, Yale School of Medicine, 135 College Street, Suite 101, New Haven, CT 06510. E-mail: email@example.com. Cardiology in Review: July/August 2020 - Volume 28 - Issue 4 - p 208-212 doi: 10.1097/CRD.0000000000000298 Buy Metrics Abstract Despite recent advances in drug-eluting stent (DES) technology, late adverse events remain concerns after percutaneous coronary intervention. The persistence of polymer material on DES has been suggested as a trigger for chronic inflammation. The Firehawk, a novel DES, has a unique design with recessed abluminal grooves, to which sirolimus and biodegradable polymer are applied. The Firehawk stent is designed to minimize polymer volume and antiproliferative drug concentration to reduce inflammation and hypersensitivity reactions. Several recent trials have reported the clinical outcomes of this device. This article provides a review of the current clinical evidence concerning the Firehawk stent. Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.