Review ArticlesPeripartum Cardiomyopathy Incidence, Risk Factors, Diagnostic Criteria, Pathophysiology, and Treatment OptionsZagelbaum, Nicole K. MD; Bhinder, Jasjit MD; Gupta, Chhaya Aggarwal MD; Frishman, William H. MD; Aronow, Wilbert S. MDAuthor Information From the Department of Medicine and Cardiology Division, Westchester Medical Center and New York Medical College, Valhalla, NY. Disclosure: The authors have no conflicts of interest to report. Correspondence: Wilbert S. Aronow MD, FACC, FAHA, Westchester Medical Center, Macy Pavilion, Room 141, Valhalla, NY 10595. E-mail: [email protected]. Cardiology in Review: May/June 2020 - Volume 28 - Issue 3 - p 148-155 doi: 10.1097/CRD.0000000000000249 Buy Metrics Abstract Peripartum cardiomyopathy is a rare and a severe form of heart failure that affects women during pregnancy or shortly after delivery. Risk factors include advanced age, race, multiparity, multifetal pregnancy, socioeconomic disparity, and medical comorbidities including systemic hypertension, diabetes, asthma, and anemia. Peripartum cardiomyopathy is associated with increased morbidity and mortality, as well as a detrimental long-term impact on quality of life. Its etiology is not clear, although it is thought to be a combined effect of a hyperdynamic fluid state associated with pregnancy, hormonal changes unique to gestation, and a genetic predisposition. There is no current expert consensus on an optimal treatment regimen. This article will provide a comprehensive review and update on this important disease state. Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.