Review ArticlesVulnerable Plaque A Review of Current Concepts in Pathophysiology and ImagingKhan, Mohammed Hasan MD; Rochlani, Yogita MD; Yandrapalli, Srikanth MD; Aronow, Wilbert S. MD; Frishman, William H. MDAuthor Information From the Cardiology Division, Department of Medicine, New York Medical College and Westchester Medical Center, Valhalla, NY. Disclosure: The authors have no conflicts of interest to report. Correspondence: Wilbert S. Aronow, MD, Cardiology Division, Westchester Medical Center and New York Medical College, 100 Woods Road, Macy Pavilion, Room 141, Valhalla, NY 10595. E-mail: firstname.lastname@example.org. Cardiology in Review: January/February 2020 - Volume 28 - Issue 1 - p 3-9 doi: 10.1097/CRD.0000000000000238 Buy Metrics Abstract Advances in our understanding of the natural history and biology of atherosclerotic vascular disease led to the concept of a vulnerable plaque (VP), which is predisposed toward more rapid progression and acute coronary events. With newer technologies, we now have at our disposal high-quality imaging studies, both invasive and noninvasive, which promise in identifying plaque characteristics that make it more vulnerable. Upcoming trials aim to evaluate the utility of imaging VP in predicting clinical events. We discuss the role of VP imaging in managing atherosclerotic vascular disease. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.