Third-Generation LVADs Has Anything Changed?Levine, Avi MD; Gass, Alan MDCardiology in Review: November/December 2019 - Volume 27 - Issue 6 - p 293–301 doi: 10.1097/CRD.0000000000000268 Symposium Buy Abstract Author InformationAuthors Article MetricsMetrics The field of durable left ventricular assist devices has advanced dramatically since its introduction into the clinical realm. From the first-generation pulsatile HeartMate XVE device to the second-generation continuous axial flow HeartMate-2 to the current third-generation centrifugal flow devices, the left ventricular assist device has undergone significant evolution. This review describes the technology and its changes over the course of time, with a focus on the fundamental question: Has anything changed? From the Division of Cardiology, Department of Medicine, New York Medical College/Westchester Medical Center, Valhalla, NY. Disclosure: Alan Gass acts as a Speaker’s Bureau, Medtronic, Speaker's Bureau, Abbott. Correspondence: Avi Levine, MD, Division of Cardiology, Department of Medicine, Westchester Medical Center, 100 Woods Road, Valhalla, NY 10595. E-mail: Elliot.Levine@wmchealth.org. Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.