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Premature Ventricular Contractions and Cardiomyopathy

You, Cindy X. MD; Liu, Christopher F. MD

doi: 10.1097/CRD.0000000000000262
Symposium
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Premature ventricular contractions (PVCs) are a common arrhythmia that may cause symptoms of variable severity. PVCs have recently garnered interest in their ability to induce adverse structural heart remodeling in an entity known as PVC-induced cardiomyopathy. This entity is a retrospective diagnosis that likely remains under-recognized and may occur concurrently with other forms of cardiomyopathy. The appropriate identification and management of PVCs in the setting of associated cardiomyopathy may have a significant impact on cardiac function and the clinical course, including recovery of left ventricular ejection fraction and improvement in patient functional status. Treatment consists of catheter ablation and/or antiarrhythmic drug therapy, but continued monitoring and follow-up are required, as the recurrence of high PVC burden may lead to redevelopment of cardiomyopathy.

From the Division of Cardiology, Department of Medicine, Weill Medical College of Cornell University, New York–Presbyterian Hospital, New York, NY.

Disclosure: The authors have no conflicts of interest to report.

Correspondence: Christopher F. Liu, MD, Division of Cardiology, Department of Medicine, Weill Medical College of Cornell University, New York–Presbyterian Hospital, 520 East 70th Street, Starr Pavilion, New York, NY 10021. E-mail: chl7001@med.cornell.edu.

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