Review ArticlesAssociation of Aging, Arterial Stiffness, and Cardiovascular Disease: A ReviewVeerasamy, Murugapathy MBBS, MRCP*‡; Ford, Gary A. FRCP*†; Neely, Dermot FRCP§; Bagnall, Alan PhD, MRCP*‡; MacGowan, Guy MD, FRCP‡; Das, Rajiv MD, MRCP‡; Kunadian, Vijay MBBS, MD, FRCP*‡Author Information From the *Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle-upon-Tyne, United Kingdom; †Institute of Ageing and Health, Faculty of Medical Sciences, Newcastle University, Newcastle-upon-Tyne, United Kingdom; ‡Cardiothoracic Centre, Freeman Hospital, Newcastle-upon-Tyne Hospitals NHS Foundation Trust, Newcastle-upon-Tyne, United Kingdom; §Department of Biochemistry, Newcastle-upon-Tyne Hospitals NHS Foundation Trust, Newcastle-upon-Tyne, United Kingdom. Disclosure: The authors have no conflicts of interest to report. The research was supported by the National Institute for Health Research (NIHR) Newcastle Biomedical Research Centre based at Newcastle-upon-Tyne Hospitals NHS Foundation Trust and Newcastle University. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR, or the Department of Health. Correspondence: Vijay Kunadian, MBBS, MD, FRCP, FACC, FESC, Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, 3rd Floor William Leech Building, Newcastle-upon-Tyne NE2 4HH, United Kingdom. E-mail: email@example.com. Cardiology in Review: September/October 2014 - Volume 22 - Issue 5 - p 223-232 doi: 10.1097/CRD.0000000000000009 Buy Metrics Abstract Coronary heart disease (CHD) is the leading cause of morbidity and mortality in the western world. Primary and secondary prevention strategies have improved tremendously. Conventional risk factors are identified and treated with intensive pharmacotherapy. Despite these measures, the incidence of CHD is on the rise in developed countries. Arterial stiffness has been identified as an independent risk factor for the development of CHD, both in the general population and in those with established CHD. This review examines the association of arterial stiffness with cardiovascular disease. © 2014 by Lippincott Williams & Wilkins.