Review ArticleThe Effect of Diet on Endothelial FunctionDavis, Nichola MD, MS*; Katz, Stuart MD, MPH†; Wylie-Rosett, Judith EdD, RD‡Author Information From the *Department of Medicine, Division of General Internal Medicine, and the ‡Department of Epidemiology & Population Health, Division of Health, Behavior, & Nutrition, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY; and the †Department of Medicine, Division of Cardiology, Yale University School of Medicine, New Haven, Connecticut. Correspondence: Nichola Davis, MD, MS, 1300 Morris Park Avenue, Mazer Bldg. 216, Bronx, NY 10461. E-mail: firstname.lastname@example.org. Cardiology in Review: March-April 2007 - Volume 15 - Issue 2 - p 62-66 doi: 10.1097/01.crd.0000218824.79018.cd Buy Metrics Abstract Endothelial dysfunction is an early precursor to atherosclerosis. Lifestyle interventions, including diet, have been shown to affect endothelial function. High-fat diets have been shown to impair endothelial function, and diets such as the Mediterranean diet have been associated with improved endothelial function. This review discusses the effects of diet, dietary supplements such as folic acid, polyphenols, and antioxidant vitamins on endothelial function. We provide a summary of the current data linking diet with endothelial function and explore controversies within this field. © 2007 Lippincott Williams & Wilkins, Inc.