Original ArticlePrediction of Moderate or Severe Pulmonary Hypertension by Main Pulmonary Artery Diameter and Main Pulmonary Artery Diameter/Ascending Aorta Diameter in Pulmonary EmbolismSanal, Shirin MD; Aronow, Wilbert S. MD; Ravipati, Gautham MD; Maguire, George P. MD; Belkin, Robert N. MD; Lehrman, Stuart G. MDAuthor Information From the Department of Medicine, Divisions of Pulmonary/Critical Care and Cardiology, Westchester Medical Center/New York Medical College, Valhalla, New York. Reprints: Wilbert S. Aronow, MD, Cardiology Division, New York Medical College, Macy Pavilion, Room 138, Valhalla, NY 10595. E-mail: [email protected]. Cardiology in Review: September 2006 - Volume 14 - Issue 5 - p 213-214 doi: 10.1097/01.crd.0000181619.87084.8b Buy Metrics Abstract We investigated the accuracy of computed tomographic measurements of main pulmonary artery diameter (MPAD) and of MPAD/ascending aorta diameter (AAD) in predicting moderate or severe pulmonary hypertension in 190 patients with acute pulmonary embolism. A pulmonary artery systolic pressure of ≥50 mm Hg measured by Doppler echocardiography was considered moderate or severe pulmonary hypertension. A MPAD of >28.6 mm and a MPAD/AAD ratio of ≥1.00 measured by computed tomography were considered abnormal. A MPAD of >28.6 mm had a 75% sensitivity and specificity, a 52% positive predictive value, a 89% negative predictive value, a 3.0 likelihood ratio for a positive test, and a 0.33 likelihood ratio for a negative test in predicting moderate or severe pulmonary hypertension. A MPAD/AAD ratio of ≥1.00 had a 59% sensitivity, a 82% specificity, a 55% positive predictive value, a 84% negative predictive value, a 3.3 likelihood ratio for a positive test, and a 0.50 likelihood ratio for a negative test. © 2006 Lippincott Williams & Wilkins, Inc.