Case ReportCardiac Sarcoidosis With Primary Involvement of the Tricuspid ValveGoyal, Sanjeev B. MD, FACE; Aragam, Jayashri R. MD, FACCAuthor Information From *Cardiac Electrophysiology, Fallon Clinic, and the Department of Medicine, University of Massachusetts Medical Center, Worcester, Massachusetts; and †Echocardiography, West Roxbury VA Medical Center, and the Department of Medicine, Harvard Medical School, West Roxbury, Massachusetts. Reprints: Sanjeev B. Goyal, MD, Department of Cardiology, Fallon Clinic, 20 Worcester Center Blvd., Worcester, MA 01608. E-mail: [email protected]. Cardiology in Review: September 2006 - Volume 14 - Issue 5 - p e12-e13 doi: 10.1097/01.crd.0000181620.57608.09 Buy Metrics Abstract Sarcoid granulomas usually involve the myocardium with rare focal extensions into the pericardium and endocardium with resultant conduction defects, ventricular arrhythmias, and ventricular systolic and diastolic dysfunction. Primary involvement of valvular leaflets resulting in valvular regurgitation or stenosis is not known. We present a case of a wastewater consultant who developed tricuspid regurgitation and symptomatic atrioventricular block secondary to infiltration of tricuspid leaflets and conduction system from sarcoid granulomas. The patient later developed severe dilated cardiomyopathy as a result of extensive cardiac sarcoidosis necessitating cardiac transplantation. Valvular regurgitation should be included as one of the presenting manifestations of cardiac sarcoidosis. © 2006 Lippincott Williams & Wilkins, Inc.