Original ArticlePrevalence of Left Ventricular Hypertrophy in Persons With and Without Obstructive Sleep ApneaSukhija, Rishi MD*; Aronow, Wilbert S. MD*; Sandhu, Rasham MD*; Kakar, Priyanka MD*; Maguire, George P. MD*; Ahn, Chul PhD†; Lehrman, Stuart G. MD*Author Information From the *Department of Medicine, Divisions of Pulmonary/Critical Care and Cardiology, Westchester Medical Center/New York Medical College, Valhalla, New York, and the †Department of Medicine, University of Texas School of Medicine at Houston, Houston, Texas. Reprints: Wilbert S. Aronow, MD, Cardiology Division, New York Medical College, Macy Pavilion, Room 138, Valhalla, NY 10595. E-mail: WSAronow@aol.com. Cardiology in Review: July-August 2006 - Volume 14 - Issue 4 - p 170-172 doi: 10.1097/01.crd.0000184455.52778.00 Buy Metrics Abstract We investigated the prevalence of left ventricular hypertrophy (LVH) in persons with and without obstructive sleep apnea (OSA). Fifty-three persons had a nocturnal polysomnogram to diagnose OSA and 2-dimensional echocardiograms to measure left ventricular mass. OSA was considered mild if the respiratory disturbance index (RDI) was 5 to 15, moderate if the RDI was 15 to 30, and severe if the RDI was >30. LVH was diagnosed if the left ventricular mass index was >110 g/m2 in women and >134 g/m2 in men. LVH was present in 21 of 27 persons (78%) with moderate or severe OSA, in 6 of 13 persons (46%) with mild OSA, and in 3 of 13 persons (23%) with no OSA (P < 0.001 comparing moderate or severe OSA with no OSA and P < 0.05 comparing moderate or severe OSA with mild OSA). OSA was a significant independent predictor of LVH after controlling the confounding effects of hypertension with an odds ratio of 3.579 (95% confidence interval, 1.589–8.058). © 2006 Lippincott Williams & Wilkins, Inc.