ArticleRole of Infection in Atherosclerosis and Coronary Artery Disease: A New Therapeutic Target?FRISHMAN, WILLIAM H. MD*; ISMAIL, ANJUM MD†Author Information *Department of Medicine and Pharmacology New York Medical College/Westchester Medical Center, Valhalla, New York †Heart Institute of Nevada, Las Vegas, Nevada Address correspondence to: William H. Frishman, MD, Department of Medicine, Munger 263, New York Medical College, Valhalla, NY 10595. Cardiology in Review: July-August 2002 - Volume 10 - Issue 4 - p 199-210 Buy Abstract There is growing evidence that inflammatory processes may be involved in the development of atherosclerosis and its complications. Viral and bacterial pathogens have been implicated as possible causative factors in the pathogenesis of coronary artery disease and postangioplasty restenosis. Antibiotic trials have been completed examining which treatment of infection can prevent the complications of coronary artery disease. In high-risk patients, the results of these most recent studies have not revealed any benefit of treatment. © 2002 Lippincott Williams & Wilkins, Inc.