Coronary Heart DiseaseCoronary Magnetic Resonance AngiographyBOTNAR, RENÉ M. PhD1,3; STUBER, MATTHIAS PhD1,3; DANIAS, PETER G. MD, PhD1; KISSINGER, KRAIG V. RT(MR)1,2; BÖRNERT, PETER PhD1,4; MANNING, WARREN J. MD1,2Author Information 1Department of Medicine, Cardiovascular Division; 2Department of Radiology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA; 3Philips Medical Systems, Best, The Netherlands; 4Philips Research, Hamburg, Germany Address reprint requests to: René M. Botnar, PhD, Cardiac MR Center, Beth Israel Deaconness Medical Center, 330 Brookline Avenue, Boston, MA 02215. Date of acceptance: September 26, 2000. Cardiology in Review: March-April 2001 - Volume 9 - Issue 2 - p 77-87 Buy Abstract Despite advances in both prevention and treatment, cardiovascular disease remains the leading cause of morbidity and mortality in the United States. The current gold standard for the diagnosis of coronary artery disease is the x-ray coronary angiogram, which is both costly and associated with a small risk of morbidity. More than 1 million Americans are referred for this test annually, and despite the availability of numerous noninvasive tests to identify patients with coronary artery disease, ≥35% of patients referred for this test are found not to have disease. It therefore would be beneficial to use a noninvasive test to allow the presence of coronary atherosclerosis to be determined directly. Coronary magnetic resonance angiography, a technique that is aimed at establishing a noninvasive test for the assessment of significant coronary stenoses, obviates the risks of patient exposure to radiation of x-ray angiography and therefore represents a major step forward in diagnostic cardiology. © 2001 Lippincott Williams & Wilkins, Inc.