TherapyABCs of Cardiovascular Disease Risk ManagementBRAUNSTEIN, JOEL B. MD; CHENG, ALAN MD; FAKHRY, CAROLE BA; NASS, CAITLIN M. NP; VIGILANCE, CAMILLE MD; BLUMENTHAL, ROGER S. MD, FACCAuthor Information Ciccarone Center for Prevention of Heart Disease, The Johns Hopkins University School of Medicine, Baltimore, Maryland This article was supported in part by an unrestricted educational grant from Merck & Co., Inc., Rahway, NJ. Address reprint requests to: Roger S. Blumenthal, MD, FACC, The Johns Hopkins Hospital, 600 North Wolfe Street, Carnegie 538, Baltimore, MD 21205. Date of acceptance: October 25, 2000. Cardiology in Review: March-April 2001 - Volume 9 - Issue 2 - p 96-105 Buy Abstract The past 20 years have witnessed a marked decline in morbidity and mortality from cardiovascular disease. This decline has been due in large part to advances in coronary risk factor modification and a better understanding of the atherosclerotic process. Compelling scientific and clinical trial evidence proves that comprehensive risk factor modification extends patient survival and reduces cardiovascular and cerebrovascular events. This article reviews the ABCs of optimal medical and lifestyle management in patients with documented atherosclerotic vascular disease as well as in those adults who are at increased risk for the development of cardiovascular disease, based on contemporary clinical trial evidence. © 2001 Lippincott Williams & Wilkins, Inc.