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Depressive Symptoms and Health-Related Quality of Life Among Prostate Cancer Survivors

Huang, Chiung-Yu PhD; Wang, Ming-Jai MSN; Lin, Yu-Hua PhD; Chen, Chun-I PhD

doi: 10.1097/NCC.0000000000000420

Background: Prostate cancer is a global health problem; its incidence is on the rise in Chinese and usually fraught with both physical and psychological symptomatology.

Objective: The aim of this study is to explore the relationships among demographic and disease characteristics, resourcefulness, depressive symptoms, and health related quality of life (HRQOL).

Methods: A descriptive, correlational design was used. A total of 200 individuals with prostate cancer were recruited. The participants completed a self-report regarding their depressive symptoms and HRQOL. Using a structural equation modeling approach, all relationships among the factors, mediators, depressive symptoms, and HRQOL were analyzed.

Results: The more resourcefulness that participants perceived, the more likely they were to report better HRQOL. The best-fitted structural equation model included individual demographics and disease characteristics and resourcefulness as significant predictors of HRQOL. Moreover, this structural model explained 72%, 76%, and 57% of the variance in physical quality of life, mental quality of life, and depressive symptoms, respectively. In addition, resourcefulness had a positive mediating effect on increasing the physical and mental quality of life and decreasing the depressive symptoms for patients with prostate cancer.

Conclusions: Resourcefulness helps patients with prostate cancer build a positive attitude and that it is crucial for enhancing the HRQOL of patients. By using the proper resourcefulness strategy, that is, either personal (self-help) or social (help-seeking), nursing professionals can substantially contribute to enhancing the HRQOL for patients with PC.

Implications for Practice: Knowledge of risk factors for HRQOL would be useful for nursing professional in detecting health problems and treatment options.

Author Affiliations: Department of Nursing, College of Medicine (Drs Huang and Lin), and Department of Industrial Management, College of Management (Dr Chen), I-Shou University, Kaohsiung; and Department of Oncology (Ms Wang), Chi-Mei Medical Center, Liouying, Taiwan.

The authors have no funding or conflicts of interest to disclose.

Correspondence: Chiung-Yu Huang, PhD, RN, Department of Nursing, I-Shou University, No. 8, Yida Rd, Yanchao District, Kaohsiung 82445, Taiwan (

Accepted for publication May 19, 2016.

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