ARTICLESQuality of Life for Long-Term Survivors of Cancer: INFLUENCING VARIABLESPedro, Leli W. DNSc, RNC, OCNAuthor Information Leli W. Pedro, DNSc, RNC, OCN, is Assistant Professor at Loma Linda University School of Nursing, California. Address correspondence and reprint requests to Leli W. Pedro, DNSc, RNC, OCN, Loma Linda University School of Nursing, 11262 Campus Street, Loma Linda, CA 92354. E-mail: firstname.lastname@example.org Accepted for publication September 25, 2000. Cancer Nursing: February 2001 - Volume 24 - Issue 1 - p 1-11 Buy Abstract The study’s purpose was to describe the relations among self-esteem, learned resourcefulness, and social support, and to show how they predict health-related quality of life (HRQL) for long-term survivors of cancer. With advances in oncology and increased survival, variables influencing the HRQL of long-term survivors of cancer must be explored. The design was descriptive and correlational. Five instruments were sent to 456 long-term survivors in southern California. Data were analyzed for 62 of 111 consenting individuals, most of whom were married, retired, white, college-educated, female survivors of breast cancer older than 60 years of age treated by radiation and surgery. Subjects with higher self-esteem reported higher HRQL (r = 0.69;p = 0.00). Learned resourcefulness had a significant negative relation with HRQL (r = −0.32;p = 0.01). Social support was operationalized as functional components, network properties, and recent loss. Only the loss component of social support had a significant negative relation with HRQL (r = −0.38;p = 0.00). Together, the three variables explained more than half of the variance (R2 = 0.53) of HRQL, with self-esteem being the strongest predictor. The HRQL of long-term survivors of cancer may increase with interventions such as both survivor-and nurse-led support groups aimed at supporting and improving self-esteem. In addition, education to anticipate social support losses may further enhance HRQL. © 2001 Lippincott Williams & Wilkins, Inc.