Special Focus: Sports MedicineAnalysis of National Football League preseason injuries resulting in roster cuts: a retrospective reviewBaker, Hayden P. MDa; Volchenko, Elan BAb; Rossi, David BAb; Dayton, Steven R. BAc; Tjong, Vehniah K. MDcAuthor Information aDepartment of Orthopaedic Surgery, The University of Chicago, Chicago, Illinois bDepartment of Orthopaedic Surgery, The University of Illinois College of Medicine, Chicago, Illinois cDepartment of Orthopaedic Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois Financial Disclosure: The authors report no conflicts of interest. Correspondence to Hayden P. Baker, MD, Department of Orthopaedic Surgery, The University of Chicago, 5758 S. Maryland Avenue, Dept 4B, Chicago, IL, USA 60637 Tel: +224-406-6176; fax: +773-702-5434; e-mail: [email protected]. Current Orthopaedic Practice: January/February 2021 - Volume 32 - Issue 1 - p 1-5 doi: 10.1097/BCO.0000000000000946 Buy Metrics Abstract Background: The National Football League (NFL) schedule consists of 16 regular season games and four additional preseason games each season. The structure of the NFL preseason allows franchises to evaluate 90 players in four games to determine which 53 should make the final roster. The purpose of this study was to investigate preseason injuries in NFL players and to identify risk factors for being cut from NFL teams after preseason injury. Methods: This study was a retrospective review of all injuries suffered by NFL athletes during the 2014 through 2019 NFL preseasons. The data were compiled using publicly available injury reports published on multiple websites. Results: We identified 110 injuries during the period of study involving players that were later cut from an NFL team during the preseason. The incidence of a preseason injury before being cut from the team was 1.59 per 1000 athletic exposures. The majority of NFL players who were cut after being injured were undrafted free agents (69 players, 63%). Rookies (38 players, 35%) most commonly were cut after being injured. Most athletes cut from NFL teams after preseason injury did not play another year in the NFL (82 players, 75%). The lower extremity was the most frequently injured body area, accounting for 45% (49 players) of all injuries. Conclusions: No prior NFL experience and being undrafted in the NFL draft were two common characteristics identified among athletes that sustained preseason injury and were later cut from the roster. Level of Evidence: Level III. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.