We report here a case of chronic eosinophilic pneumonia with significant endobronchial involvement. A 59-year-old man was admitted complaining of fever, productive cough, wheezing, and dyspnea. There were ground-glass opacities in bilateral upper fields and tram track shadows in the left lower lung field on chest x-ray, and ground-glass opacities in bilateral upper lobes, thickening of the bronchial walls, and centrilobular nodules on computed tomographic scan of the chest. There was marked eosinophilia in the peripheral blood and bronchoalveolar lavage fluid and was diagnosed as chronic eosinophilic pneumonia. Bronchoscopy also revealed white nodules at the orifice of the right S6 and the left S1+2 bronchi. The histologic examination of these nodules revealed eosinophilic inflammation into the bronchial wall. This is a rare case of chronic eosinophilic pneumonia with endobronchial eosinophilic involvement.
*Department of Respiratory Medicine
†Department of Pathology, Ishikawa Prefectural Central Hospital
‡Department of Respiratory Medicine, Cellular Transplantation Biology, Kanazawa University Graduate School of Medicine, Kanazawa, Ishikawa, Japan
Disclosure: The authors have no conflicts of interest to report.
Reprints: Johsuke Hara, MD, PhD, Department of Respiratory Medicine, Ishikawa Prefectural Central Hospital, 2–1, Kuratsuki-Higashi, Kanazawa, Ishikawa, 920-8530, Japan (e-mail: firstname.lastname@example.org).
Received February 12, 2011
Accepted February 21, 2011