Analytical Methods and Statistical MethodsUsefulness and feasibility of repeated tail artery cannulations in the ratKumagai, Kosukea,,b; Toyooka, Terushigeb; Otsuka, Yoheib; Horikawa, Masahiroc; Yamada, Kentaroc; Tomiyama, Aratab; Takeuchi, Satorub; Kurihara, Koichia; Wada, KojirobAuthor Information aFourth Division, Aeromedical Laboratory, Japan Air Self-Defense Force, Sayama bDepartment of Neurosurgery, National Defense Medical College, Tokorozawa, Saitama, Japan cCharles T. Dotter Department of Interventional Radiology, Oregon Health and Science University, Portland, Oregon, USA Received 26 September 2020 Accepted 27 November 2020 Supplemental Digital Content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's website, www.bpmonitoring.com. Correspondence to Kosuke Kumagai, PhD, Forth Division, Aeromedical Laboratory, Japan Air Self-Defense Force, 2-3 Inariyama, Sayama, Saitama 350 1324, Japan, Tel: +81 4 2953 6131; e-mail: [email protected] Blood Pressure Monitoring: June 2021 - Volume 26 - Issue 3 - p 230-233 doi: 10.1097/MBP.0000000000000522 Buy SDC Metrics Abstract Rat ventral caudal artery (VCA, tail artery) cannulation for blood pressure monitoring and blood sampling is essential for maintaining consistent procedures in rat models. Double or triple insults are sometimes necessary, but repeated VCA cannulations have not been compared with repeated femoral artery cannulations. In addition, the collateral system for resistance to ischemia in the rat tail is unclear. Our present study revealed that repeated VCA cannulations on different days was a better technique than repeated femoral artery cannulations in terms of surgical time, postsurgical weight loss and ischemic complications. Furthermore, the lateral caudal arteries and the segmental anastomosing vessels were important for resistance to ischemic complications after VCA occlusion. Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.