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Compartment syndrome of the forearm with life-threatening bleeding after fasciotomy as the presenting sign of postpartum acquired hemophilia A

a case report

Van Laer, Mariea; Penaloza, Andreaa; Stockman, Willemc; Meert, Philippea; Lambert, Catherineb; Hermans, Cédricb

Blood Coagulation & Fibrinolysis: April 2019 - Volume 30 - Issue 3 - p 120–126
doi: 10.1097/MBC.0000000000000799
CASE REPORT
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Acquired hemophilia A (AHA) is a rare bleeding disorder caused by the development of autoantibodies against clotting factor VIII. Although the cause of this disorder remains obscure, it is often linked to malignancies, drug administration, autoimmune diseases and pregnancy. In pregnancy-associated AHA, hemorrhagic symptoms usually present 1–4 months peripartum, however they may occur up to 1-year postpartum. Compartment syndrome of the forearm is also very uncommon complication of AHA but can have devastating consequences. We report a rare case of a compartment syndrome of the forearm in a 30-year-old woman 2.5 months postpartum as the presentation of pregnancy-associated AHA.

aDivision of Emergency Medicine

bDivision of Hematology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels

cDivision of Critical Care Medicine, AZ Delta Hospital, Roeselare, Belgium

Correspondence to Cédric Hermans, MD, PhD, FRCP (Lon, Edin), Division of Adult Haematology, St-Luc University Hospital, Avenue Hippocrate 10, 1200 Brussels, Belgium Tel: +32 2 64 17 85/+32 2 764 17 40; fax: +32 2 764 89 59; e-mail: cedric.hermans@uclouvain.be,hermans.cedric@gmail.com

Received 4 July, 2018

Revised 1 February, 2019

Accepted 1 February, 2019

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