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Thrombosis in pediatric malignancy

a review and future perspectives with focus on management

Bordbar, Mohammadreza; Karimi, Mehran; Shakibazad, Nader

Blood Coagulation & Fibrinolysis: November 2018 - Volume 29 - Issue 7 - p 596–601
doi: 10.1097/MBC.0000000000000772
REVIEW ARTICLES
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Venous thromboembolism (VTE) result in significant morbidity and mortality in children with cancer. The cause of VTE in children with cancer is multifactorial and includes genetic predisposition (thrombophilia), disease-related factors, and treatment-related factors including use of central venous catheter (CVC), surgery, and chemotherapy. This review aims to examine current knowledge regarding the incidence, risk factors, clinical manifestation, evaluation, prevention, and management of thromboembolic events in children with cancer.

Hematology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

Correspondence to Nader Shakibazad, MD, Hematology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. Tel: +98 9362663809; e-mail: nshakibazad@gmail.com

Received 26 May, 2018

Accepted 11 August, 2018

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