CASE REPORTVenous thromboembolism in HIV-positive women during puerperium: a case seriesJansen, J Marijea; Lijfering, Willem Mb; Sprenger, Herman Gc; van der Meer, Janb; van Pampus, Maria GaAuthor Information aDepartment of Obstetrics and Gynaecology, The Netherlands bDivision of Haemostasis, Thrombosis and Rheology, The Netherlands cDivision of Infectious Diseases, University Medical Center Groningen, Groningen, The Netherlands Received 7 May, 2007 Revised 8 October, 2007 Accepted 16 October, 2007 Correspondence to Dr Maria G. van Pampus, MD, PhD, Department of Obstetrics and Gynaecology, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands Tel: +31 503612791; fax: +31 503611806; e-mail: firstname.lastname@example.org Blood Coagulation & Fibrinolysis: January 2008 - Volume 19 - Issue 1 - p 95-97 doi: 10.1097/MBC.0b013e3282f38c23 Buy Metrics Abstract Several studies in the past few years suggested that HIV-infection is associated with an increased risk of venous thromboembolism. No data have been reported, however, on pregnancy and the postpartum period as possible additional risk factors for venous thromboembolism in HIV-infected women. We present a cohort of 41 consecutive pregnant HIV-infected women, wherein three cases (7.3%) had venous thromboembolism within 3 months postpartum. Annual incidence was 313 per 1000 person-years (95% confidence interval, 65–915). This risk is 120 fold higher than in HIV-positive controls, whereas the risk is 157-fold higher compared to HIV-negative pregnant women. Further clinical studies are warranted to assess its implications for pregnancy and postpartum management in HIV-infected women. © 2008 Lippincott Williams & Wilkins, Inc.