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Negative pressure dressing for promoting wound healing of purpura fulminans in a newborn with homozygous protein C deficiency

Chuansumrit, Ampaiwana; Kanogsunthornrat, Nirobolb; Sirachainan, Nongnucha; Porapakpenjun, Surapand; Chantarukha, Rujineeb; Warrasak, Sukhumac; Wongwerawattanakoon, Pakawanb

Blood Coagulation & Fibrinolysis: January 2007 - Volume 18 - Issue 1 - p 77–79
doi: 10.1097/MBC.0b013e3280120e16
CASE REPORTS
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A negative pressure dressing to promote wound healing of purpura fulminans in a girl aged 35 days with homozygous protein C deficiency is reported. Two wounds of 11 × 11 cm2 at the abdominal wall and 14 × 14 cm2 at the left trunk were covered with sterile sponges embedded with a multiple-hole drain tube and transparent plastic film. The exposed end of the drain was then connected to the wall suction apparatus to create negative pressure at −120 mmHg. The dressing was changed every 2 days. Within 4–6 weeks, the wounds were completely healed and skin grafting was not required.

aDepartment of Pediatrics, Thailand

bDepartment of Nursing, Thailand

cDepartment of Ophthalmology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

dDepartment of Pediatrics, Maharaj Nakhornratchasima Hospital, Nakhornratchasima, Thailand

Received 10 August, 2006

Accepted 15 October, 2006

Correspondence and requests for reprints to Prof. Ampaiwan Chuansumrit, MD, Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Rama VI Road, Bangkok 10400, Thailand Tel/fax: +662 2011748; e-mail: raajs@mahidol.ac.th

© 2007 Lippincott Williams & Wilkins, Inc.