Challenging Bleeders - A Symposium for Haemostasis Specialists: Proceedings of the Edinburgh Haematology Symposium; November 8-9 2002, Edinburgh, UK: ReviewFactor VII deficiencyPerry, David J.Section Editor(s): Ludlam, Christopher Author Information Haemophilia Centre and Haemostasis Unit, Royal Free and University College Medical School, Pond Street, Hampstead, London, UK. Correspondence and requests for reprints to D. J. Perry, Haemophilia Centre and Haemostasis Unit, Royal Free and University College Medical School, Pond Street, Hampstead, London NW3 2QG, UK. Tel: +44 (0)207 830 2068; e-mail: D.email@example.com Blood Coagulation & Fibrinolysis: June 2003 - Volume 14 - Issue - p S47-S54 Buy Abstract As yet, there have been neither systematic reviews nor reports of randomized, controlled trials involving factor VII (FVII) deficiency. Hence, a picture of this disorder can only be drawn by reviewing and summarizing the data that is available. This article provides an overview of the understanding of this rare, inherited disorder of coagulation. In particular, the status of current knowledge of the disorder's prevalence, clinical presentation, diagnostic characteristics and molecular genetics is reviewed, followed by a summary of currently available options for its treatment and management. © 2003 Lippincott Williams & Wilkins, Inc.