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Prostate Cancer: Localized: Surgical Therapy II (PD19): Podium 19: Saturday, September 11, 2021

PD19-01 AGE-STRATIFIED CONTINENCE OUTCOMES OF ROBOTIC-ASSISTED RADICAL PROSTATECTOMY

Sadri, Iman; Arezki, Adel; Zakaria, Ahmed; Couture, Félix; Nguyen, David-Dan; Karakiewicz, Pierre; Zorn, Kevin

doi: 10.1097/JU.0000000000002008.01
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INTRODUCTION AND OBJECTIVE:

Incontinence after robot-assisted radical prostatectomy (RARP) significantly impacts quality of life. This study aims to compare the age-stratified continence outcomes in men undergoing RARP.

METHODS:

A retrospective review was performed on a prospectively maintained database of 1737 patients who underwent RARP for localized prostate cancer between 2007 and 2019. Patients were stratified into five groups based on age: group 1, ≤54 years (n=245); group 2, 55-59 years (n=302) ; group 3, 60-64 years (n=386); group 4, 65-69 years (n=348); and group 5, ≥70 years (n=116). Functional outcomes were assessed up to 36 months. Log-rank and multivariable Cox regression analyses were performed to compare the time to recovery of pad-free continence by age group.

RESULTS:

Continence rates of groups 1 to 5 were respectively 90.2%, 79.1%, 80.4%, 71.4%, and 59.8% at one-year follow-up (p<0.001). After 3 years, groups 1 through 5 had continence rates of 97%, 91.7%, 89.3%, 81.4%, and 77.6%, respectively (p<0.001). Median time to recovery of continence was 58, 135, 140, 152 and 228 days, respectively. Among men who remained incontinent, older patients consistently required more pads. In Cox proportional hazard model, groups 2, 3, 4 and 5 were respectively 33% (p<0.001), 34% (p<0.001), 33% (p=0.001), and 41% (p=0.005) more likely to remain incontinent compared to group 1.

CONCLUSIONS:

Age is associated with significantly lower rates of continence recovery, longer time to recovery of continence, and more severe cases of incontinence after RARP.

Source of Funding:

none

© 2021 by American Urological Association Education and Research, Inc.