Robert Warriner, III, MD, FCCP, ABPM/UHM, CWS, is Chief Medical Officer, Praxis Clinical Services, Anaheim, CA, and Emeritus Medical Director, Southeast Texas Center for Wound Care and Hyperbaric Medicine, Conroe Regional Medical Center, Conroe, TX.

Robert Burrell, PhD, is Professor and Chair, Department of Biomedical Engineering, and Faculty, Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada. This paper is based on their lecture at the 19th Annual Clinical Symposium on Advances in Skin and Wound Care, October 2, 2004, Phoenix, AZ. ADV SKIN WOUND CARE 2005;18(Suppl 1):2-12.