CASE REPORTEvaluating the Effectiveness of a Novel Skin Barrier Protectant in a Patient with Acute Radiodermatitis of the Vulva: A Case ReportVan Bever, Leen BSc; Claes, Stefan BSc; Robijns, Jolien PhD, MSc; Censabella, Sandrine PhD, MSc; Pannekoeke, Luc BSc; Van de Werf, Evelyn MD; Bulens, Paul MDAuthor Information At the Limburg Oncology Center, Jessa Hospital, Hasselt, Belgium, Leen Van Bever, BSc, and Stefan Claes, BSc, are radiotherapy nurses and Jolien Robijns, PhD, MSc, is a postdoctoral fellow. At Hasselt University, Jolien Robijns, PhD, MSc, is a postdoctoral fellow, Faculty of Medicine and Life Sciences. At Jessa Hospital, Sandrine Censabella, PhD, MSc, is a clinical psychologist, Department of Medical Oncology. At the Limburg Oncology Center, Luc Pannekoeke, BSc, is a radiotherapy nurse; and Evelyn Van de Werf, MD, and Paul Bulens, MD, are radiotherapists. Acknowledgments: Leen Van Bever discloses a speaker agreement with 3M. The dressings used in this study were provided by the manufacturer free of charge. The authors have disclosed no other financial relationships related to this article. Submitted January 27, 2020; accepted in revised form March 4, 2020. Advances in Skin & Wound Care: January 2021 - Volume 34 - Issue 1 - p 49-55 doi: 10.1097/01.ASW.0000722768.95461.82 Buy Metrics Abstract OBJECTIVE To evaluate the use of a novel skin barrier protectant in a patient treated with radiotherapy for vulvar cancer. METHODS This case report was conducted in a radiotherapy department with two women undergoing radiotherapy for vulvar carcinoma. A novel skin barrier protectant was evaluated in one patient; the other underwent the institutional standard skin care protocol. Skin reactions and pain were evaluated using the Radiotherapy Oncology Group Criteria. MAIN RESULTS The patient who was treated with the skin protectant showed accelerated healing toward the end of radiotherapy, and this was accompanied with a decrease in pain (maximum pain score 6/10). In comparison, the patient treated with the standard skin care protocol had an extended healing process, experienced a higher pain level (maximum pain score 9/10), and required more nursing care. CONCLUSIONS This case report is the first to suggest that this novel skin barrier protectant could effectively manage acute radiodermatitis in patients with cancer. This case report hopes to lay the foundation for future randomized controlled trials with a larger and broader patient population. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.