Digital ulcers are a serious complication in 50% of patients with scleroderma. These ulcers have the potential to resist conventional therapies. There have been several reviews of scleroderma care over the last 5 years, but there are new developments in this field that advance clinician knowledge. This review provides an overview of previous digital ulcer management and a concise summary of new peer-reviewed literature on the topic since 2015 to provide guidance to practitioners and researchers seeking well-supported and novel/off-label therapies to consider.
In the Department of Dermatology, University of Texas Medical Branch at Galveston, Keith D. Wagner, MD, MS, is a resident physician; Kate Woolridge, MD, is a dermatology resident graduate; and Ashley Group, MD, is Associate Professor of Dermatology.
The authors have disclosed no financial relationships related to this article.
Submitted December 1, 2018; accepted in revised form January 29, 2019; published ahead of print October 26, 2019.
Online date: October 29, 2019