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Nontoxic Three-Part Combination Local Wound Therapy to Eradicate Carbapenem-Resistant Klebsiella pneumoniae

Kim, Nicholas, MD; Murphy, Mary, RN; Choudry, Umar, MD

doi: 10.1097/01.ASW.0000546119.25057.53

ABSTRACT This case report describes eradication of carbapenem-resistant Klebsiella pneumoniae from an ischial pressure injury in a patient who underwent a 3-week course of nontoxic three-part combination local wound therapy. With this therapy, providers prevented systemic spread of this multidrug-resistant pathogen and avoided the nephrotoxicity associated with conventional triple antibiotic therapy.

In Minneapolis, Minnesota, Nicholas Kim, MD, is Assistant Professor, Division of Plastic Surgery, University of Minnesota; Mary Murphy, RN, is a Certified Wound Ostomy Continence Nurse, Minneapolis Veterans Affairs Health Care System; and Umar Choudry, MD, is Associate Professor, Division of Plastic Surgery, University of Minnesota. Acknowledgements: The authors thank Adam Zuchowski, BS, for his assistance with the manuscript. The authors have disclosed no financial relationships related to this article. Submitted March 1, 2018; accepted May 21, 2018.

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