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Abstracts: ASAIO Cardiac Abstracts


Stewart, Robert1; Hannan, Robert2; Balk, Steven1; Ybarra, Marion2; Ojito, Jorge2; Burke, Redmond2; Kung, Robert1

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The HeartBooster™ is a minimally invasive cardiac assist device capable of either univentricular, or biventricular cardiac support. This is accomplished by external compression of the heart, resulting in an artificial cardiomyoplasty device. Because of the non-blood contacting nature of the HeartBooster™ design, issues related to device scaling to much smaller sizes, which are highly problematic for conventional VAD designs, are not significant (with the HeartBooster™ design). A pediatric version of the HeartBooster ™ (PediBooster) was constructed and tested. The HeartBooster™ design was scaled to 1/3 of its adult size, resulting in a 4 cm diameter device. Using a mock physiologic flow loop, flows up to 1 LPM were achieved with the PediBooster using a pneumatic drive pressure of 8 psi, and an assist rate of 80 beats per minute. In a small animal (porcine) model, heart failure (resulting in a 50% reduction in cardiac output (to 1.2 LPM)) was induced pharmocologically, and the PediBooster was initiated to provide greater than 50% flow enhancement (up to 2 LPM). Key issues for success include device fit and placement, and precise synchonization of device actuation with the reduced ventricular contraction. In addition, intermittent actuation was achieved for weaning. Because of its minimally invasive nature, the PediBooster device may be an ideal support device for neonates following complex cardiac reconstructions. A device is being further developed for univentricular support following surgical palliation for hypoplastic left heart syndrome.

Copyright © 2005 by the American Society for Artificial Internal Organs