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Abstracts: ASAIO Cardiac Abstracts

NEW PULSATILE, PERCUTANEOUS, PORTABLE, EXTRACOPOREAL CARDIO-PULMONARY BYPASS PUMP(T-PLS®;TWIN-PULSE LIFE SUPPORT) FOR THREE-STAGE TREATMENT OF CARDIOGENIC SHOCK PATIENTS

Min, B G1,2,3; Won, Y S2,3; Shin, J S2,3; Sun, K2

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New electromechanical, pulsatile and percutaneous cardiopulmonary bypass system(T-PLS) was developed and applied in sixty surgical safety/efficacy clinical trials, and in ten emergency applications of cardiogenic shock patients. In shock cases, three-stage treatment were performed using a single T-PLS(Twin-Pulse Life Support) from coronary angiography, to surgery (PTCA or mid-cap CABG), and to recovery. This pulsatile and portable pump(30kg) were used as PCPS(percutaneous cardiopulmonary support) in surgery/angio room, and as mid-term ECMO in ICU during the recovery period. The high pulse pressure of the dual-pump blood flows were shown to improve the tissue perfusion (as measured in renal and coronary arteries) with increased urine output, and the washout effects on the oxygenator membrane surfaces were produced by the higher peak pressures and peak flows than the non-pulsatile pumps and IABP. T-PLS provided the natural waveforms of pulse-pressure (40–60mmHg) in arterial side, and self-synchronization was observed between the pump flow and LV ejection, as the aortic-valve were closed by high pulse pump pressure. The Seldinger-type cannulae of Fv (21 fr.) and Fa (17 Fr.) could provide pump flows of 3–4 l/min in 60–75 kg patients. The four floating polyurethane valves and the alternating roller’s mild pushing on the twin-blood sacs could produce high-energy pulsatile flows with oxygenation without hemolysis and thrombosis problems in seventy clinical trials.

Copyright © 2005 by the American Society for Artificial Internal Organs