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Abstracts: ASAIO Cardiac Abstracts

ECG TRIGGERED PUSATILE BYPASS IN A PIGLET MODEL

Tallman, R1; Olshove, V2; Gomez, D2; McConnell, P4; Cassidy, S3; Weinstein, S2

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Objective:

Pulsatile perfusion during cardiopulmonary bypass (CPB) has not been widely used clinically. The use of an ECG triggered pulsatile pump offers the promise of adding a pulse wave at timed intervals during CPB while the heart is contracting. The purpose of this study was to evaluate the pulse characteristics of ECG triggered pulsatile bypass in a piglet model.

Methods:

7 piglets were used (5.0 - 6.4 Kg). Through a median sternotomy, the aorta (8 Fr) and right atrium (18 Fr) were cannulated. The CPB circuit used of a Jostra HL-20 roller pump, oxygenator, and ¼“ venous and art. lines. CPB target flow was 1.8 l/min/m2. ”Co-pulsation“ pulsed at systolic ejection and ”counter-pulsation“ triggered after ejection. Hemodynamic power (HP) and energy equivalent pressure (EEP) were compared to the mean atrerial pressure and reported as % difference.

Results and Conclusions:

Despite timing off the R and T-waves respectively, actual peak HP and pressures were delivered in diastole for co-pulsation (EEP = 48.9 ± 2.03 mmHg, 11%) (fig 1) and in systole during counter-pulsation (EEP = 47.2 ± 1.48 mmHg, 10.3%). Considerable variability was seen in pulse pressure and HP which may be a limitation of the roller pump (fig. 1).

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Copyright © 2005 by the American Society for Artificial Internal Organs