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Abstracts: ASAIO Bioengineering/tissue Engineering Abstracts


Rademacher, Lindsey M1; Manning, Keefe B1; Fontaine, Arnold A1; Deutsch, Steven1

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Atherosclerosis (stenosis), which is the narrowing of a blood vessel, can result from plaque build-up and may cause severe reduction in blood flow. In this experiment, steady and pulsatile flow through a symmetric stenosis is examined. Data is obtained within a glass stenosis model using particle image velocimetry (PIV). PIV uses two lasers that flash within microseconds of each other to illustrate small (10 μm) particles added to the fluid. Images are captured using a PIV camera that flashes at a frequency of approximately 3 Hz. The images are processed, using commercial PIV software, providing 2-component velocities in the image plane. For steady flow experiments, data is acquired both upstream and downstream of the stenosis at three different Reynolds numbers (50 <500), yielding laminar, transitional, and turbulent profiles. For pulsatile flow experiments, data is acquired at various points in the pulsatile cycle at three different beat rates (60, 70, and 80 bpm). The data obtained is compared on the basis of vortex shedding seen downstream of the stenosis. The vortices are generated due to the jet behavior of the fluid as it passed through the stenosis. The strength of the shed vortices are determined by calculating the vortex circulation. Numerical comparison of the steady and pulsatile flow data are made and discussed.

Copyright © 2005 by the American Society for Artificial Internal Organs