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Vascular Complications and Use of a Distal Perfusion Cannula in Femorally Cannulated Patients on Extracorporeal Membrane Oxygenation

Ranney, David N.*; Benrashid, Ehsan*; Meza, James M.*; Keenan, Jeffrey E.*; Bonadonna, Desiree; Mureebe, Leila; Cox, Mitchell W.; Daneshmand, Mani A.*

doi: 10.1097/MAT.0000000000000656
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Femoral arterial cannulation in adult venoarterial (VA) extracorporeal membrane oxygenation (ECMO) predisposes patients to ipsilateral limb ischemia. Placement of a distal perfusion catheter (DPC) is one of few techniques available to prevent or manage this complication. Although frequently used, the indications for and timing of DPC placement are poorly characterized, and no guidelines are available to guide its use. The purpose of this study was to compare the incidences of vascular complications and limb ischemia between patients who did and did not receive a DPC at the time of primary ECMO cannulation. Between June 2009 and April 2015, 132 adults underwent VA ECMO cannulation at our institution. Of the 80 femoral cannulations comprising this retrospective single-center study cohort, 14 (17.5%) received a DPC at the time of primary cannulation. Demographics, indications for ECMO, and cardiovascular history and risk factors were not significantly different between comparison groups. Median arterial cannula size was 17 French in both groups. Vascular complications occurred in 2 of the 14 patients with initial DPC (14.3%) compared with 21 of 66 without initial DPC (31.8%; p = 0.188). Limb ischemia occurred in 2 of 14 patients in the DPC group (14.3%) and 15 of 66 in the non-DPC group (22.7%; p = 0.483). In-hospital mortality was comparable between groups. DPC placement at the time of primary cannulation may lower the incidence of limb ischemia. The benefit of DPC placement once evidence of limb ischemia is apparent remains unclear.

From the *Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina; Perfusion Services, Duke University Medical Center, Durham, North Carolina; and Division of Vascular Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina.

Submitted for consideration February 2017; accepted for publication in revised form August 2017.

Disclosures: The authors have no conflicts of interest to report.

Correspondence: Mani A. Daneshmand, Duke University Medical Center 3867, Durham, NC 27710. Email:

Copyright © 2018 by the American Society for Artificial Internal Organs