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LVAD Outflow Graft Role in Pump Thrombosis

Barac, Yaron D.; Nevo, Adam; Schroder, Jacob N.; Milano, Carmelo A.; Daneshmand, Mani A.

doi: 10.1097/MAT.0000000000000936
Review Article: PDF Only

Left ventricular assist devices are (LVAD) used for circulatory support in patients with end-stage heart failure. Hemolysis/pump dysfunction is a well-known complication of this therapy with various etiologic causes. A small proportion of these complications are caused by outflow graft obstructions; this complication has received little attention in the scientific literature. Herein, we provide a comprehensive overview of the role of the LVAD outflow graft obstruction and its treatment options.

From the Division of Cardiothoracic Surgery, Duke University Medical Center, Durham, North Carolina.

Submitted for consideration April 2018; accepted for publication in revised form October 2018.

Disclosure: The authors have no conflicts of interest to report.

Yaron D. Barac and Adam Nevo contributed equally to this manuscript.

Correspondence: Mani A. Daneshmand, Duke University Medical Center 3867, Durham, NC 27705. Email:

Copyright © 2019 by the American Society for Artificial Internal Organs