From the *Mechanical and Aerospace Engineering Department, University of California San Diego, La Jolla, California
†Division of Cardiovascular Medicine, University of California San Diego, La Jolla, California
‡Department of Cardiology, Clinical Sciences, Lund University and Skane University Hospital, Lund, Sweden
§Department of Cardiology, Hospital General Universitario Gregorio Marañón, Facultad de Medicina, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañón, and CIBERCV, Madrid, Spain
¶Department of Mechanical Engineering, San Diego State University, San Diego, California; and
‖Jacobs School of Engineering, Institute for Engineering in Medicine, University of California San Diego, La Jolla, California.
Submitted for consideration October 2019; accepted for publication in revised form February 2020.
Disclosure: L.R., P.M.-L., J.B., A.M.K., and J.C.d.A. are inventors of methods for quantifying intracardiac stasis and shear-mediated hemolysis from imaging data submitted under PCT and US patent applications (PCT/US2016/063626 and PCT/US19/026146). The other authors have no conflicts of interest to report.
This work has been supported by the National Institutes of Health / UC Center for Accelerated Innovation and the American Heart Association via grants NIH NCAI-UCCAI-2017-06-6 and AHA 16GRNT27250262.
Supplemental digital content is available for this article. Direct URL citations appear in the printed text, and links to the digital files are provided in the HTML and PDF versions of this article on the journal’s Web site (www.asaiojournal.com).
Present address for Juan C. del Alamo: Center for Cardiovascular Biology, Mechanical Engineering Department, University of Washington, 850 Republican St, Seattle, WA 98109. Email: [email protected].
Correspondence: Juan C. del Alamo, Mechanical and Aerospace Engineering Department, 9500 Gilman Drive, La Jolla, CA 92093. Email: [email protected] or Andrew M. Kahn, UCSD Sulpizio Cardiovascular Center, 9452 Medical Center Drive, La Jolla, CA 92037. Email: [email protected].
