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Highlights from the Extracorporeal Life Support Organization Registry


Nasr, Viviane G.*; Raman, Lakshmi; Barbaro, Ryan P.; Guner, Yigit#; Tonna, Joseph; Ramanathan, Kollengode; PAPPALARDO, FEDERICO§; Thiagarajan, Ravi R.**; Alexander, Peta M.A.**,†† on behalf of the ELSO Registry Scientific Oversight Committee

doi: 10.1097/MAT.0000000000000863
Review Article

Extracorporeal membrane oxygenation (ECMO) is a supportive therapy for patients with severe cardiovascular or respiratory failure refractory to conventional medical therapy. Improvements in ECMO technology, easy access to ECMO devices, and a greater understanding of care of ECMO patients have led to increased utilization of ECMO. The Extracorporeal Life Support Organization (ELSO) registry was established in 1984, to collect data on patients receiving ECMO support to help improve outcomes of these patients. The registry has grown to include over 400 contributing centers from 60 countries with data for more than 90,000 patients. Many investigators have used the ELSO registry to answer clinical questions on outcomes and care of this vulnerable patient population. This report provides a brief summary of 16 peer-reviewed articles that have advanced the knowledge and treatment of neonates, children, and adults supported with ECMO using data from the ELSO registry.

From the *Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts

Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas

Department of Pediatrics, C.S. Mott Children’s Hospital, Ann Arbor, Michigan

§Department Cardiothoracic ICU, Advanced Heart Failure and Mechanical Circulatory Support Program, Vita Salute University, San Raffaele Hospital, Milan, Italy

Division of Emergency Medicine, Division of Cardiothoracic Surgery, University of Utah School of Medicine, Utah

Department of Cardiac Thoracic and Vascular Surgery, National University Heart Center, National University Hospital, Singapore

#Division of Pediatric Surgery, Department of Surgery, Children’s Hospital of Orange County, University of California Irvine Medical Center, Orange, California

**Department of Cardiology, Boston Children’s Hospital, Boston, Massachusetts

††Department of Pediatrics, Harvard Medical School, Boston, Massachusetts.

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Submitted for consideration May 2018; accepted for publication in revised form June 2018.

Disclosure: The authors have no conflicts of interest to report.

Correspondence: Viviane G. Nasr, Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children’s Hospital, Harvard Medical School, Boston, MA 02115. Email:

Copyright © 2019 by the American Society for Artificial Internal Organs