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Left Ventricular Distension in Veno-arterial Extracorporeal Membrane Oxygenation

From Mechanics to Therapies

Rajagopal, Keshava

doi: 10.1097/MAT.0000000000000789
Review Article
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Veno-arterial (V-A) extracorporeal membrane oxygenation (ECMO) is increasingly commonly used to treat acute cardiac or pulmonary failure because of a wide range of etiologies. However, despite progressively improving outcomes, the mortality associated with V-A ECMO, particularly when used to treat cardiac failure (its most common indication), continues to be high. Consistent with this, V-A ECMO is associated with numerous morbid complications. Left ventricular (LV) distension is a major complication of V-A ECMO, and is challenging both to treat and diagnose. The author review the pathophysiology underlying LV distension, and construct a systematic diagnostic and therapeutic approach.

From the Department of Advanced Cardiopulmonary Therapies and Transplantation, University of Texas-Houston McGovern Medical School and Memorial Hermann-Texas Medical Center, Houston, Texas.

Submitted for consideration November 2017; accepted for publication in revised form February 2018.

Disclosure: The author have no conflicts of interest to report.

Correspondence: Keshava Rajagopal, Department of Advanced Cardiopulmonary Therapies and Transplantation, University of Texas-Houston McGovern Medical School and Memorial Hermann-Texas Medical Center, 6400 Fannin, Suite 2350, Houston, TX 77030. Email: keshava.rajagopal@uth.tmc.edu.

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