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Clinical Design Functions: Round Table Discussions on the Bioengineering of Liquid Ventilators

Costantino, Maria Laura*; Micheau, Philippe; Shaffer, Thomas H.; Tredici, Stefano§; Wolfson, Marla R.

doi: 10.1097/MAT.0b013e318199c167
Respiratory Support

During the 6th International Symposium on Perfluorocarbon Application and Liquid Ventilation, a round table discussion on bioengineering was held in which different experts shared their opinions and experiences about the use of a total liquid ventilator design for clinical applications. To structure the discussion, all experts were invited to contribute their knowledge within the context of three matrixes related to the liquid ventilators: 1) function and technology, 2) ventilation modes, and 3) risk analyses. The outcome of this international conference recommends continued development of a total liquid ventilator toward clinical applications.

From the *Department of Structural Engineering, Politecnico di Milano, Piazza Leonardo da Vinci, Milano, Italy; †Department of Mechanical Engineering, Université de Sherbrooke, Sherbrooke, Québec, Canada; ‡Department of Research, Nemours Research Lung Center, Wilmington, Delaware; §Department of Surgery, University of Michigan, Ann Arbor, Michigan; and ¶Departments of Physiology, Pediatrics and Medicine, Temple University School of Medicine, Philadelphia.

Submitted for consideration June 2008; accepted for publication in revised form December 2008.

Reprint Requests: Philippe Micheau, PhD, Department of Mechanical Engineering, Université de Sherbrooke, 2500 Blvd. de l’Université, Sherbrooke, Quebec, Canada, J1K 2R1. Email:

Copyright © 2009 by the American Society for Artificial Internal Organs